Use of diazepam in treatment of severe convulsive status epilepticus.

نویسندگان

  • M J Parsonage
  • J W Norris
چکیده

Quantitative determination of the cells excreted in the urine has until recently been regarded as a cumbersome and timeconsuming procedure (Lancet, 1961). Houghton and Pears (1957) attempted to simplify the technique, and McGeachie and Kennedy (1963) described a method of semi-quantitative cell counting which was suitable for routine use yet was much more accurate than the ordinary wet-film technique. In the course of a recent study of renal function after surgery (Lindsay et al., 1965) it was observed that there was a considerable difference between urinary white cell excretion rates before and after surgery in many patients, so further investigation of this was undertaken.

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منابع مشابه

Evidence-Based Guideline: Treatment of Convulsive Status Epilepticus in Children and Adults: Report of the Guideline Committee of the American Epilepsy Society.

CONTEXT The optimal pharmacologic treatment for early convulsive status epilepticus is unclear. OBJECTIVE To analyze efficacy, tolerability and safety data for anticonvulsant treatment of children and adults with convulsive status epilepticus and use this analysis to develop an evidence-based treatment algorithm. DATA SOURCES Structured literature review using MEDLINE, Embase, Current Conte...

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Convulsive status epilepticus in children: Etiology, treatment protocol and outcome

This study aimed to determine the etiology, treatment protocol and outcome of convulsive status epilepticus (SE) in children. An institutional treatment protocol using benzodiazepines (diazepam and midazolam) was assessed in a retrospective case study. The treatment protocol (Ege Pediatric Status Epilepticus Protocol or EPSEP) was developed based on an operational definition of pediatric SE acc...

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Treatment of status epilepticus in children.

Status epilepticus is a medical emergency requiring immediate treatment. General treatment is aimed at restoring physiologic homeostasis, and drug therapy is aimed at arresting the convulsive activity and preventing its recurrence. Concurrent administration of diazepam and either phenytoin or phenobarbital will be effective in most cases. After the status epilepticus has been treated the underl...

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A comparison of four treatments for generalized convulsive status epilepticus. Veterans Affairs Status Epilepticus Cooperative Study Group.

BACKGROUND AND METHODS Although generalized convulsive status epilepticus is a life-threatening emergency, the best initial drug treatment is uncertain. We conducted a five-year randomized, double-blind, multicenter trial of four intravenous regimens: diazepam (0.15 mg per kilogram of body weight) followed by phenytoin (18 mg per kilogram), lorazepam (0.1 mg per kilogram), phenobarbital (15 mg ...

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Lorazepam vs diazepam for pediatric status epilepticus: a randomized clinical trial.

IMPORTANCE Benzodiazepines are considered first-line therapy for pediatric status epilepticus. Some studies suggest that lorazepam may be more effective or safer than diazepam, but lorazepam is not Food and Drug Administration approved for this indication. OBJECTIVE To test the hypothesis that lorazepam has better efficacy and safety than diazepam for treating pediatric status epilepticus. ...

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عنوان ژورنال:
  • British medical journal

دوره 3 5557  شماره 

صفحات  -

تاریخ انتشار 1967